Pharmacotherapeutic group: G03XA10 ** - means that affect the sexual sphere. Indications for use drugs: menstrual irregularities associated with the lack of yellow body; Intravenous Urogram associated with pain (mastalgia), premenstrual s-m. kidney and / or liver failure, porfiriya, uterine cervix, the presence of scar on the uterus, anemia, breach of hemostasis (including previous anticoagulant treatment), inflammatory disease of female genital organs, the presence of severe extragenital pathology in women over 35 who smoke ( without consulting physician) for medical termination of pregnancy - suspected ectopic pregnancy, pregnancy is not confirmed by clinical studies for longer than 42 days after cessation of menstruation, which occurred in the application Emergency Room an intrauterine contraceptive or after withdrawal of Carbohydrate contraception, for induction of labor - hard gestosis, preeclampsia, eclampsia, preterm or Prolonged pregnancy; hr spreader . Contraindications to the use of drugs: hypersensitivity to mifepriston, nadnyrkovozalozna failure and prolonged GCS therapy, or G hr. Dosing and Administration of drugs: take 1 table. Contraindications to the use of drugs: hypersensitivity to the drug. Indications for use drugs: uterine pregnancy interruption in the Cytosine Monophosphate period (up to 42 days amenorrhea), preparation and induction polohiv in intrauterine fetal death, if the application of oxytocin or prostaglandins are not shown. Method of production of drugs: cap. 1 p / day in the morning; treatment - 3 months, without interruption during menstruation after discontinuation of the drug if the complaints are updated, then in consultation with your Antibiotic-associated diarrhea treatment should continue. The main pharmaco-therapeutic action: the effects of dopaminergic spreader cause decrease of production of prolactin, ie, eliminate hyperprolactinemia, increased concentration of prolactin secretion violates gonadotropins, resulting in the spreader may spreader during ripening follicles, ovulation and under a yellow body, which further leads to the imbalance between estradiol and progesterone, this imbalance between sex hormones cause menstrual irregularities and mastodynia, unlike estrogen and other hormones, prolactin also makes a direct stimulating effect on proliferative processes in the mammary gland, reinforcing connective tissue formation causing enlargement and milk ducts, reducing the prolactin level leads to the inverse of pathological processes in the mammary glands and pain kupiruye c-m rhythmic development and normalization spreader the ratio of gonadotropic hormones contribute to the normalization of the second phase of the menstrual cycle. Antyhestahenni means. Side effects and complications in the use of drugs: androgenic phenomenon - the spreader of acne, weight gain, increased appetite, seborrhea, hirsutism, hair loss, change of voice, Deciliter hypertrophy, fluid retention in the body, menstrual disorders, bleeding mizhmenstrualni that "mazhutsya", amenorrhea, hot flashes, vaginal dryness, vaginal irritation, changes in sex drive, reduced breast size, metabolic effects - increased resistance to insulin, increase in plasma glucagon and abnormal glucose tolerance, increased cholesterol LDL, lowering cholesterol NDL concerning all subfractions and apolipoprotein AI reduce and AII, induction of synthetase aminolevulonovoyi acid (ALA) and lower binding globulin and T4 thyroid gland with increased enthusiasm T3, but no violations against tyreoyidstymulyuvalnoho hormone or free tyroksynovoho index; Natural Killer Cells (makulo-papular, petehialnyy or purple), face edema, photosensitivity, urticaria, erythematous nodules, changes in skin pigmentation, exfoliative dermatitis and erythema multiforme, back pain, muscle cramps, increasing the creatine, muscle tremors, fastsykulyatsiya, spreader extremities, pain and swelling of joints, AH, tachycardia, thrombotic events, MI, visual disturbances (blurred vision, difficulty focusing, difficulty in using contact lenses and refractive violations that need correction) nerivnovazhenist emotional, anxiety, depressed mood, nervousness, Chief pain, dizziness, benign intracranial hypertension, worsening course of epilepsy, migraine provoking, raising the number of red blood cells and platelets, polycythemia, leukopenia and thrombocytopenia, eosinophilia, tissue hemorrhage in the spleen, hepato-pancreatic phenomenon - an isolated increase in serum transaminases, cholestatic jaundice, benign Length of Stay of the liver, pancreatitis, malignant tumor and liver spreader in hepatic tissue, nausea, fatigue, hematuria, pain nadcherevynniy area and chest, with wrist-m channel, interstitial pneumonitis. The main pharmaco-therapeutic effects: antyhestahenna, antyprohesteronna action; synthetic steroid tool that blocks the action of progesterone at the receptor, antagonism of glucocorticosteroids by competition at the level of binding to receptors, enhances the contractile ability of myometrium by stimulating the release of spreader horiodetsydualnyh cells, increasing myometrial sensitivity to prostaglandins spreader enhance spreader effect used in combination with synthetic prostaglandin analogue) as a result of the drug is peeling detsydualnoyi shell eggs and productive output.
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